Acute pain, spinal cord, such as occurs with trauma, often has a reversible cause and may require only transient measures and correction of the underlying problem. In contrast, chronic pain often results from conditions that are difficult to diagnose and treat, and that may take a long time to reverse. Examples being cancer, spinal cord, neuropathy, and referred pain. Often, pain pathways come into play that continue to transmit the sensation of pain even though the underlying condition or injury that originally caused pain has been resolved. In such situations, the pain has to be managed with a multimodal approach.
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